Curriculum Vitae  Google Scholar


Xiuyu Ma, Keegan Korthauer, Christina Kendziorski, Michael A. Newton. A compositional model to assess expression changes from single-cell RNA-seq data. bioRxiv, doi: 10.1101/655795, 2019.

Keegan Korthauer, Rafael A Irizarry. Genome-wide repressive capacity of promoter DNA methylation is revealed through epigenomic manipulation. bioRxiv, doi: 10.1101/381145, 2018.

peer reviewed journal articles

Keegan Korthauer, Patrick K Kimes, Claire Duvallet, Alejandro Reyes, Ayshwarya Subramanian, Mingxiang Teng, Chinmay Shukla, Eric J Alm, and Stephanie C Hicks. A practical guide to methods controlling false discovery rates. Genome Biology, 20:118. doi: 10.1186/s13059-019-1716-1, 2019.

David Y Takeda, Sándor Spisák, Ji-Heui Seo, Connor Bell, Edward O’Connor, Keegan Korthauer, Dezső Ribli, István Csabai, Norbert Solymosi, Zoltán Szállási, David R Stillman, Paloma Cejas, Xintao Qiu, Henry W Long, Viktória Tisza, Pier Vitale Nuzzo, Mersedeh Rohanizadegan, Mark M Pomerantz, William C Hahn, Matthew L Freedman. A somatically acquired enhancer of the androgen receptor is a noncoding driver in advanced prostate cancer. Cell, Jul 12;174(2):422-432.e13. doi: 10.1016/j.cell.2018.05.037, 2018.

Keegan Korthauer, Sutirtha Chakraborty, Yuval Benjamini, Rafael A Irizarry. Detection and accurate False Discovery Rate control of differentially methylated regions from Whole Genome Bisulfite Sequencing. Biostatistics, kxy007. doi: 10.1093/biostatistics/kxy007, 2018.

Chinmay J Shukla, Alexandra L McCorkindale, Chiara Gerhardinger, Keegan D Korthauer, Moran N Cabili, David M Shechner, Rafael A Irizarry, Philipp G Maass, John L Rinn. High-throughput identification of RNA nuclear enrichment sequences. The EMBO Journal, 37:e98452. doi: 10.15252/embj.201798452, 2018.

Jeea Choi, Shuyun Ye, Kevin H Eng, Keegan Korthauer, William H Bradley, Janet S Rader, Christina Kendziorski. IPI59: an actionable biomarker to improve treatment response in serous ovarian carcinoma patients. Statistics in Biosciences, 9(1):1-12. doi: 10.1007/s12561-016-9144-1, 2017.

Keegan D Korthauer, Li-Fang Chu, Michael A Newton, Yuan Li, James Thomson, Ron Stewart, Christina Kendziorski. A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biology, 17:222. doi: 10.1186/s13059-016-1077-y, 2016.

Clara Bodelon, Svetlana Vinokurova, Joshua N Sampson, Johan A den Boon, Joan L Walker, Mark A Horswill, Keegan Korthauer, Mark Schiffman, Mark E Sherman, Rosemary E Zuna, Jason Mitchell, Xijun Zhang, Joseph F Boland, Anil K Chaturvedi, S Terence Dunn, Michael A Newton, Paul Ahlquist, Sophia S Wang, Nicolas Wentzensen. Copy number alterations and HPV integration in cervical precancer and invasive cancer. Carcinogenesis, 37(2):188-196. doi: 10.1093/carcin/bgv171, 2016.

Keegan Korthauer, Christina Kendziorski. MADGiC: a model-based approach for identifying driver genes in cancer. Bioinformatics, 31(10): 1526–1535. doi: 10.1093/bioinformatics/btu858, 2015.

Yun Ju Sung, Keegan D Korthauer, Michael D Swartz, Corinne D Engelman. Methods for Collapsing Multiple Rare Variants in Whole Genome Sequencing Data. Genetic Epidemiology, 38(S1):S13-S20. doi:, 2014.

Marcel Wüthrich, Karen Ersland, John C Pick-Jacobs, Benjamin H Gern, Christopher A Frye, Thomas D Sullivan, Meghan B Brennan, Hanna I Filutowicz, Kevin O’Brien, Keegan D Korthauer, Stacey Schultz-Cherry, Bruce S Klein. Limited model antigen expression by transgenic fungi induces disparate fates during differentiation of adoptively transferred T cell receptor transgenic CD4+ T cells: robust activation and proliferation with weak effector function during recall. Infection and immunity, 80(2): 787-797. doi: 10.1128/IAI.05326-11 2012.

Donna Z Bliss, Jaclyn Lewis, Keegan Hasselmann (now Korthauer), Kay Savik, Ann Lowry, Robin Whitebird. Use and evaluation of disposable absorbent products for managing fecal incontinence by community-living people. Journal of wound, ostomy, and continence nursing, 38(3):289. doi: 10.1097/WON.0b013e31821530ca, 2011.

Lin Wang, Raka M Mitra, Keegan D Hasselmann (now Korthauer), Masanao Sato, Lisa Lenarz-Wyatt, Jerry D Cohen, Fumiaki Katagiri, Jane Glazebrook. The genetic network controlling the Arabidopsis transcriptional response to Pseudomonas syringae pv. maculicola: roles of major regulators and the phytotoxin coronatine. Molecular plant-microbe interactions, 21(11): 1408-1420. doi: 10.1094/MPMI-21-11-1408, 2008.

book chapters

Keegan Korthauer, John Dawson and Christina Kendziorski. Predicting cancer subtypes using survival-supervised latent Dirichlet allocation models. In Advances in Statistical Bioinformatics: Models and Integrative Inference for High-Throughput Data, Kim-Anh Do, Zhaohui Steve Qin, Marina Vannucci (Eds). Cambridge University Press. doi: 10.1017/CBO9781139226448 2013.

conference proceedings

Jose A Delgado, Elizabeth A Jacobs, Nancy E Adler, Keegan Korthauer, Alicia Fernandez. The relation between subjective socioeconomic status, depression and self-rated health in a population of African Americans, Hispanics and non-Hispanic whites with diabetes, Journal of General Internal Medicine, 28: S209. doi: 10.1007/s11606-013-2436-y, 2013.

Jose Delgado, Alicia Fernandez, Nancy E Adler, Keegan Korthauer, Elizabeth Jacobs Subjective and objective socioeconomic status and control of hypertension and diabetes. Journal of General Internal Medicine, 27:S312-S312. doi: 10.1007/s11606-012-2038-0, 2012.

phd dissertation

Keegan Korthauer. Bayesian hierarchical modeling of high-throughput genomic data with applications to cancer bioinformatics and stem cell differentiation, Ph.D. Thesis, University of Wisconsin, 2015.

† = co-first authorship; these authors contributed equally
‡ = co-second authorship; these authors contributed equally