Statistical Methods for Functional Genomics - CSHL 2019

Welcome to Fun Geno!

Here, you’ll find course material for the 2019 CSHL short course on “Statistical Methods for Functional Genomics” for the modules on single-cell RNAseq and DNA methylation.

Single-cell RNA seq module

Slides

• Intro to single-cell RNA-seq (Rmd)

• Preprocessing & normalization (Rmd)

• Survey of downstream analysis methodology (Rmd)

Workflows & exercises

• Read count data:
  • Preprocessing & normalization (Rmd)
  • Downstream analysis (Rmd)
• Droplet data:
  • Preprocessing & normalization (Rmd)
  • Downstream analysis (Rmd)

DNA methylation module

Slides

• Intro to DNA methylation sequencing analysis (Rmd)

Workflows & exercises

• Binomial regression in R (Rmd)

• Exploring the regulatory capacity of DNA methylation (Rmd)

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These materials are available under a CC BY-NC-SA 4.0 license